Generic Name : Pancreatin 192 mg, Hemicellulase 50 mg, Purified bile extracts 25 mg
Preparation : Enteric Coated Tablet
Pharmacological Category : Digestive Enzyme
80 / Per 10 Tablet
Mechanism of Action (MOA)
Pancreatin contains enzymes principally amylase, lipase and protease. Lipase hydrolyzes triglycerides to fatty acids and glycerol with the help of bile salt. The amylase digests starch to oligosaccharides and glucose. The protease digests protein into oligopeptides and amino acids.
Hemicellulase is a collective term for a group of enzymes that hydrolyze hemicelluloses, a plant cell wall polymer.
Bile plays important role in fat digestion and absorption. It helps to emulsify the large fat particles into minute particles allowing the lipase to digest them. Further, it aids in absorption of the digested fat end products through the intestinal mucosal membrane.
Absorption : Enzymes get rapidly released and are available for digestion of food in intestines.
Indications and Dosage
Dose : One tablet to two tablets of PANOLASE three times a day with each meal or snack
Nausea, vomiting, abdominal discomfort (in high dose only)
Hypersensitivity to pancreatin / bile extract / hemicellulase, acute pancreatitis, acute exacerbation of chronic pancreatic diseases
Warnings / Precautions
Antacids and Cimetidine decrease the inactivation of enzyme activity.
Pregnancy Category : C
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