Salbutamol is a β2 adrenergic agonist and thus it stimulates β2 adrenergic receptors. Binding of salbutamol to the β2 receptors results in the relaxation of the bronchial smooth muscles. Salbutamol also inhibits the release of bronchoconstriction agents from the mast cells, inhibits the microvascular leakage and enhances the muciliary clearance. Bromhexine acts on the mucus at the formative stages in the glands within the mucus secreting cells. It destroys the structure of the acid mucopolysaccharide fibers in the mucoid sputum and produces less viscous mucus, which is easier to expectorate.
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