It is an imidazole derivative, interacts with yeast 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the membrane. Results in inhibits ergosterol synthesis, resulting in increased cellular permeability. Lignocaine: • local anesthetic with low index of sensitization and toxicity, • Helps to reduce pain and stinging in the ear associated with acute otitis media
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